FRACTAL STORM (SELF-LAID OPTIONS

In the LSD-bound crystal framework, the facet chain in the lid residue L209EL2 varieties intensive hydrophobic contacts with both equally LSD and surrounding residues in TMs III, IV, and V (Determine 4C). If the lid moved aside to show the binding pocket in simulation, numerous of such contacts broke. We As a result hypothesized that L209EL2 functi